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. Fakerun 3.0.2.0.crack + Serial Key Full Version Crack [2020].The compound A-93680, the chemical name of which is 2-[2-[2-[4-(aminosulfonyl)phenyl]-2-methyl-1-oxo-3-oxo-propyl]-1H-indol-3-yl]acetic acid, is a therapeutic agent for curing a disease by inhibiting angiotensin II production.
In the past, various methods for manufacturing A-93680 or its pharmaceutically acceptable salt have been proposed. For example, WO97/05020 discloses a method for manufacturing A-93680 or its pharmaceutically acceptable salt, including a step in which N-hydroxysuccinimide (NHS) is condensed with 2-[2-[2-[4-(aminosulfonyl)phenyl]-2-methyl-1-oxo-3-oxo-propyl]-1H-indol-3-yl]-acetic acid to form 2-[2-[2-[4-(aminosulfonyl)phenyl]-2-methyl-1-oxo-3-oxo-propyl]-1H-indol-3-yl]-acetic acid NHS salt. WO98/39519 discloses a process for manufacturing A-93680 or its pharmaceutically acceptable salt comprising reacting a carboxylic acid ester of a 2-(aminosulfonyl)phenylacetic acid or 2-(aminosulfonyl)phenylamide derivative in which an ester bond is introduced into the carboxylic acid side, with an amine salt in the presence of a catalyst.
U.S. Pat. No. 6,495,742 discloses a novel process for manufacturing A-93680 or its pharmaceutically acceptable salt by reacting an aminosulfonylphenylacetic acid derivative having a sulfonamide group with a base to form a base adduct of aminosulfonylphenylacetic acid derivative, and then reacting the base adduct with a hydroxy-containing compound to form a dipept
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